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Article

Antisense transcription licenses nascent transcripts to mediate transcriptional gene silencing.

Genes & development - 1 Nov 2016

Dang Yunkun, Cheng Jiasen, Sun Xianyun, Zhou Zhipeng, Liu Yi

Abstract excerpt

In eukaryotes, antisense transcription can regulate sense transcription by induction of epigenetic modifications. We showed previously that antisense transcription triggers Dicer-independent siRNA (disiRNA) production and disiRNA locus DNA methylation (DLDM) in Neurospora crassa Here we show that the conserved exonuclease ERI-1 (enhanced RNAi-1) is a critical component in this process. Antisense transcription and...

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Identifiers

PMID: 27856616
DOI: 10.1101/gad.285791.116
PMCID: PMC5131781

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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