Article
ATP-dependent chromatin remodeling shapes the long noncoding RNA landscape.
Genes & development - 1 Nov 2014
Alcid Eric A, Tsukiyama Toshio
Abstract excerpt
Long noncoding RNAs (lncRNAs) are pervasively transcribed across eukaryotic genomes, but functions of only a very small subset of them have been demonstrated. This has led to active debate about whether many of them have any biological functions. In addition, very few regulators of lncRNAs have been identified. We developed a novel genetic screen using reconstituted RNAi in Saccharomyces cerevisiae and...
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