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Article

Functions and therapeutic potential of protein phosphatase 1: Insights from mouse genetics.

Biochimica et biophysica acta. Molecular cell research - 1 Jan 2019

Ferreira Mónica, Beullens Monique, Bollen Mathieu, Van Eynde Aleyde

Abstract excerpt

Protein phosphatase 1 (PP1) catalyzes more than half of all phosphoserine/threonine dephosphorylation reactions in mammalian cells. In vivo PP1 does not exist as a free catalytic subunit but is always associated with at least one regulatory PP1-interacting protein (PIP) to generate a large set of distinct holoenzymes. Each PP1 complex controls the dephosphorylation of only a small subset of PP1 substrates. We...

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Source

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Identifiers

PMID: 30056088
DOI: 10.1016/j.bbamcr.2018.07.019
PMCID: PMC7114192

Genes

PIP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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