Article

Reactivation of p53 as a radiosensitization strategy for mutant p53 cancers treated with high-LET radiotherapy

2023-12-04

Abstract excerpt

<title>Abstract</title> <p>Radiation therapy (RT) remains a common treatment for cancer patients worldwide, despite the development of targeted biological compounds and immunotherapeutic drugs. The challenge in RT lies in delivering a lethal dose to the cancerous site while sparing the surrounding healthy tissues. Low linear energy transfer (low-LET) and high linear energy transfer (high-LET) radiations have dist...

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Literature Corpus work: b83593ff-4ff5-50ba-8c4b-33b98bf7219c
DOI: 10.21203/rs.3.rs-3574189/v1

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