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Article

Cellular and Genetic Determinants of the Sensitivity of Cancer to α-Particle Irradiation

6 Aug 2019

Abstract excerpt

Abstract Targeted α-particle–emitting radionuclides have great potential for the treatment of a broad range of cancers at different stages of progression. A platform that accurately measures cancer cellular sensitivity to α-particle irradiation could guide and accelerate clinical translation. Here, we performed high-content profiling of cellular survival following exposure to α-particles emitted from radium-223...

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Identifiers

PMID: 31387923
DOI: 10.1158/0008-5472.can-19-0859

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