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Serum-dependent recruitment of the chromatin remodeler CHD8 to promoters is mediated by the ERK-ELK pathway

2022-09-09

Abstract excerpt

<h4>ABSTRACT</h4> Chromodomain helicase DNA binding protein 8 (CHD8) is a chromatin remodeler of the SNF2 family involved in gene transcription regulation. It has been shown that CHD8 is required for cell proliferation, cell differentiation and central nervous system development. In fact, CHD8 haploinsufficiency causes a human syndrome characterized by autism, macrocephaly, gastrointestinal complaints and some ot...

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Literature Corpus work
b82fb3a7-dbb8-5a57-b027-3b49c6e5fdfd
DOI
10.1101/2022.09.09.507301
Open publication

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Serum-dependent recruitment of the chromatin remodeler CHD8 to promoters is mediated by the ERK-ELK pathwayDOI 10.1101/2022.09.09.507301
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