Article

ELK1 has a dual activating and repressive role in human embryonic stem cells

2019-07-05

Abstract excerpt

<h4>Background: </h4> The ERK MAPK pathway plays a pivotal role in regulating numerous cellular processes during normal development and in the adult but is often deregulated in disease scenarios. One of its key nuclear targets is the transcription factor ELK1, which has been shown to play an important role in controlling gene expression in human embryonic stem cells (hESCs). ELK1 is known to act as a transcription...

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Literature Corpus work: 96bf0ae9-e3e8-57f7-b788-80d36e274efa
DOI: 10.12688/wellcomeopenres.15091.2

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