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Article

Small Molecule APOL1 Inhibitors as a Precision Medicine Approach for APOL1-mediated Kidney Disease

2024-04-08

Abstract excerpt

<title>Abstract</title> <p>Chronic kidney disease affects ~10% of people worldwide and there are no disease modifying therapeutics that address the underlying cause of any form of kidney disease. Genome wide association studies have identified the G1 and G2 variants in the <italic>apolipoprotein L1 </italic>(<italic>APOL1</italic>)<italic> </italic>gene as major contributors to a subtype of proteinuric kidney dis...

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Literature Corpus work
b80118bf-13f7-5dd9-b545-af4168c670cb
DOI
10.21203/rs.3.rs-3922092/v1
Open publication

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Small Molecule APOL1 Inhibitors as a Precision Medicine Approach for APOL1-mediated Kidney DiseaseDOI 10.21203/rs.3.rs-3922092/v1
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