Article

IDH mutations in G2-3 conventional central bone chondrosarcoma: a mono institutional experience

2022-12-13

Abstract excerpt

<h4>Background: </h4> Heterozygous isocitrate dehydrogenase ( IDH ) mutations occur in about half of conventional central bone chondrosarcomas (CCBC). Aim of this study was to assess the frequency and prognostic impact of IDH mutations in high grade CCBC patients. <h4>Methods: </h4>: 64 patients with G2 and G3 CCBC were included. DNA extraction, PCR amplification of IDH1/2 exon 4s, and sequencing analysis with Sa...

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Literature Corpus work: b7d95dfe-1b76-5729-8e50-dc5cde77e841
DOI: 10.21203/rs.3.rs-2160128/v1

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