Article

Kente: A Graph-based Pangenomic Approach for Horizontal Gene Transfer Detection in Microbiomes

2026-06-26

Abstract excerpt

<h4>Motivation</h4> Horizontal gene transfer (HGT) shapes bacterial evolution and microbial ecosystems, yet detecting HGT within microbiomes remains a challenge due to fragmented metagenomic assemblies, reference bias, reliance on gene boundaries, and limited ability to model structural mosaicism and patterns across genomes. <h4>Methods</h4> We present Kente, a novel pangenome graph-based framework designed for...

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Literature Corpus work: b7d72801-56e9-517c-8e2b-e4a46b500207
DOI: 10.64898/2026.06.22.733643

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