Article
PG-SCUnK: measuring pangenome graph representativeness using single-copy and universal K-mers.
BMC bioinformatics - 30 Dec 2025
Cumer Tristan, Milia Sotiria, Leonard Alexander S, Pausch Hubert
Abstract excerpt
BACKGROUND: Pangenome graphs integrate multiple assemblies to represent non-redundant genetic diversity. However, current evaluations of pangenome graphs rely primarily on technical parameters (e.g., total length, number of nodes/edges, growth curves), which fail to assess how effectively the graph represents homologous stretches across the integrated assemblies and how well short reads align against pangenome...
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