Article

High-resolution metagenome assembly for modern long reads with myloasm

2025-09-06

Abstract excerpt

Long-read metagenome assembly promises complete genomic recovery from microbiomes. However, the complexity of metagenomes poses challenges. We present myloasm, a metagenome assembler for PacBio HiFi and Oxford Nanopore Technologies (ONT) R10.4 long reads. Myloasm uses polymorphic k-mers to construct a high-resolution string graph and then leverages differential abundance for graph simplification. On real-world ONT...

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Literature Corpus work: 3be00d64-0d20-504c-9209-5c2706b38c62
DOI: 10.1101/2025.09.05.674543

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