Article

InStrain enables population genomic analysis from metagenomic data and rigorous detection of identical microbial strains

2020-01-23

Abstract excerpt

Coexisting microbial cells of the same species often exhibit genetic differences that can affect phenotypes ranging from nutrient preference to pathogenicity. Here we present inStrain, a program that utilizes metagenomic paired reads to profile intra-population genetic diversity (microdiversity) across whole genomes and compare populations in a microdiversity-aware manner, dramatically increasing genomic compariso...

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Literature Corpus work: b7c465dc-df6b-5ea8-807b-469b0410a985
DOI: 10.1101/2020.01.22.915579

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