Article

An integrated metagenomics pipeline for strain profiling reveals novel patterns of transmission and global biogeography of bacteria

2015-11-14

Abstract excerpt

We present the Metagenomic Intra-species Diversity Analysis System (MIDAS) , which is an integrated computational pipeline for quantifying bacterial species abundance and strain-level genomic variation, including gene content and single nucleotide polymorphisms, from shotgun metagenomes. Our method leverages a database of >30,000 bacterial reference genomes which we clustered into species groups. These cover the...

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Literature Corpus work: 10aab2c3-426a-5bd5-8783-ba4b602fdbfc
DOI: 10.1101/031757

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