Article

Accurate estimation of intraspecific microbial gene content variation in metagenomic data with MIDAS v3 and StrainPGC

2024-04-10

Abstract excerpt

Metagenomics has greatly expanded our understanding of the human gut microbiome by revealing a vast diversity of bacterial species within and across individuals. Even within a single species, different strains can have highly divergent gene content, affecting traits such as antibiotic resistance, metabolism, and virulence. Methods that harness metagenomic data to resolve strain-level differences in functional pote...

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Literature Corpus work: 7a1cd01d-c6a1-5279-bc6b-dd2b66b9f2fb
DOI: 10.1101/2024.04.10.588779

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