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Article

Intraspecies associations from strain-rich metagenome samples

2025-02-08

Abstract excerpt

Genetically distinct strains of a species can vary widely in phenotype, reducing the utility of species-resolved microbiome measurements for detecting associations with health or disease. While metagenomics theoretically provides information on all strains in a sample, current strain-resolved analysis methods face a tradeoff: de novo genotyping approaches can detect novel strains but struggle when applied to stra...

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Literature Corpus work
a354dee0-e113-5888-81ae-d8011ba59589
DOI
10.1101/2025.02.07.636498
Open publication

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Intraspecies associations from strain-rich metagenome samplesDOI 10.1101/2025.02.07.636498
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