Article
Strain-resolved community genomic analysis of gut microbial colonization in a premature infant.
Proceedings of the National Academy of Sciences of the United States of America - 18 Jan 2011
Morowitz Michael J, Denef Vincent J, Costello Elizabeth K, Thomas Brian C, Poroyko Valeriy, Relman David A, Banfield Jillian F
Abstract excerpt
The intestinal microbiome is a critical determinant of human health. Alterations in its composition have been correlated with chronic disorders, such as obesity and inflammatory bowel disease in adults, and may be associated with neonatal necrotizing enterocolitis in premature infants. Increasing evidence suggests that strain-level genomic variation may underpin distinct ecological trajectories within mixed...
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