Article

ET-1 mediated vasoconstriction leads to memory impairment and synaptic dysfunction reminiscent of Alzheimer’s disease phenotype

2020-05-04

Abstract excerpt

<h4>Background: </h4> Cerebrovascular lesions seen as white matter hyperintensity in MRI of elderly population provides evidence for micro-infracts and micro-bleeds, which contribute to vascular dementia. Such vascular insult may be caused by impairment in blood flow in specific area in brain involving small vessels and these could gradually worsen the pathology leading to cognitive deficits. In the present study...

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Literature Corpus work: b7bbea14-0abb-58a2-9011-bd91e587947f
DOI: 10.21203/rs.3.rs-25345/v1

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