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Differential Left and Right Carotid Artery Blood Flow and Altered Hippocampal Mitochondrial Function After Transverse Aortic Constriction in Aging Rats

2025-01-19

Abstract excerpt

<h4>Background</h4> The hippocampus is a key brain structure that has been implicated in vascular dementia etiology and is highly sensitive to changes in cerebral blood flow. Brain hypoperfusion in cardiovascular disease may facilitate neurodegeneration in the hippocampus by limiting substrate transport and metabolism. While most animal studies have relied on artery occlusion to lower brain blood flow, brain hypo...

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Literature Corpus work
5ac7feb2-9a14-5d28-9772-99eee21f734c
DOI
10.1101/2025.01.15.633217
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Differential Left and Right Carotid Artery Blood Flow and Altered Hippocampal Mitochondrial Function After Transverse Aortic Constriction in Aging RatsDOI 10.1101/2025.01.15.633217
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