Article

Decade-long remissions of leukemia sustained by the persistence of activated CD4+ CAR T-cells

2021-05-13

Abstract excerpt

<title>Abstract</title> <p>The adoptive transfer of T lymphocytes reprogrammed to target tumor cells has demonstrated significant potential in various malignancies. However, little is known about the long-term potential and the clonal stability of the infused cells. Here, we studied the longest persisting CD19 redirected chimeric antigen receptor (CAR) T cells to date in two chronic lymphocytic leukemia (CLL) pat...

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Literature Corpus work: b7ba06eb-f6c1-5684-afee-def80209493f
DOI: 10.21203/rs.3.rs-505891/v1

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