Article

Rapid transcriptional responses to serum exposure are associated with sensitivity and resistance to antibody-mediated complement killing in invasive Salmonella Typhimurium ST313

2019-04-25

Abstract excerpt

<h4>Background: </h4> : Salmonella Typhimurium ST313 exhibits signatures of adaptation to invasive human infection, including higher resistance to humoral immune responses than gastrointestinal isolates. Full resistance to antibody-mediated complement killing (serum resistance) among nontyphoidal Salmonellae is uncommon, but selection of highly resistant strains could compromise vaccine-induced antibody immunity...

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Literature Corpus work: b797d0dc-1dd9-52fe-9fc5-04f458713436
DOI: 10.12688/wellcomeopenres.15059.1

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