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Elucidating Mechanisms of Tolerance to <i>Salmonella</i> Typhimurium Across Long-Term Infections Using the Collaborative Cross

2022-04-12

Abstract excerpt

Understanding the molecular mechanisms underlying resistance and tolerance to pathogen infection may present the opportunity to develop novel interventions. Resistance is the absence of clinical disease with low pathogen burden, while tolerance is minimal clinical disease in the face of high pathogen burden. Salmonella is a worldwide health concern. We studied 18 strains of Collaborative Cross mice that survive a...

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Literature Corpus work
d11abcfa-7c17-5c3c-8840-d6da9d425c87
DOI
10.1101/2022.04.11.487981
Open publication

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Elucidating Mechanisms of Tolerance to <i>Salmonella</i> Typhimurium Across Long-Term Infections Using the Collaborative CrossDOI 10.1101/2022.04.11.487981
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