Article
Signatures of adaptation in human invasive Salmonella Typhimurium ST313 populations from sub-Saharan Africa.
PLoS neglected tropical diseases - 1 Mar 2015
Okoro Chinyere K, Barquist Lars, Connor Thomas R, Harris Simon R, Clare Simon, Stevens Mark P, Arends Mark J, Hale Christine, Kane Leanne, Pickard Derek J, Hill Jennifer, Harcourt Katherine, Parkhill Julian, Dougan Gordon, Kingsley Robert A
Abstract excerpt
Two lineages of Salmonella enterica serovar Typhimurium (S. Typhimurium) of multi-locus sequence type ST313 have been linked with the emergence of invasive Salmonella disease across sub-Saharan Africa. The expansion of these lineages has a temporal association with the HIV pandemic and antibiotic usage. We analysed the whole genome sequence of 129 ST313 isolates representative of the two lineages and found...
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