Article
Investigation of evolutionary dynamics and genetic heterogeneity of Salmonella in persistent bacteremia.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2026
Yeh Ting-Kuang, Huang Yao-Ting, Liu Po-Yu
Abstract excerpt
BACKGROUND: Persistent and recurrent Salmonella bacteremia remains a significant clinical challenge associated with high morbidity. The pathogen's ability to adapt within the host often leads to recurrent infections, necessitating in-depth analysis to determine if genetic heterogeneity drives this persistence. This study employs whole genome sequencing and strain phasing to investigate the evolutionary dynamics...
Read the complete abstract on PubMedTopics
- Humans
- Bacteremia
- Salmonella Infections
- Genetic Heterogeneity
- Phylogeny
- Evolution, Molecular
