Article

Nr2f1 controls mitochondrial dynamics in mouse adult-born hippocampal neurons

2022-03-27

Abstract excerpt

The nuclear receptor Nr2f1 plays a key role during cortical development by acting as a strong transcriptional regulator in embryonic and postnatal neural cells. In humans, its mutations cause the Bosch-Boonstra-Schaaf optic atrophy-intellectual syndrome (BBSOAS), a rare neurodevelopmental disorder characterized by multiple clinical features including optic nerve atrophy, intellectual disability, and autistic trait...

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Literature Corpus work: b778e810-a36c-548c-839c-33f70edbbbd2
DOI: 10.1101/2022.03.25.485113

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