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Unravelling the conundrum of nucleolar NR2F1 localization: A comparative analysis of NR2F1 antibody-based approaches <i>in vitro</i> and <i>in vivo</i>

2024-01-02

Abstract excerpt

<h4>ABSTRACT</h4> As a transcription factor, NR2F1 regulates spatiotemporal gene expression during development and in adulthood. Aberrant NR2F1 causes a rare neurodevelopmental disorder known as Bosch-Boonstra- Schaaf Optic Atrophy Syndrome. In addition, altered NR2F1 expression is frequently observed in various cancers and is considered a prognostic marker or potential therapeutic target. In this context, NR2...

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Literature Corpus work
889b431c-7578-5c02-9465-35fb8ac0e007
DOI
10.1101/2023.12.31.573551
Open publication

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Unravelling the conundrum of nucleolar NR2F1 localization: A comparative analysis of NR2F1 antibody-based approaches <i>in vitro</i> and <i>in vivo</i>DOI 10.1101/2023.12.31.573551
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