Article

Cross-Ancestry Remapping of the Chromosome 1q31 Th2 pathway-associated interval Refines an Asthma Association Signal in Patients with Steroid-Dependent Disease

2026-05-15

Abstract excerpt

<h4>Background</h4> The chromosome 1q31 Th2 pathway-associated interval has been linked to asthma, but its phenotype specificity and cross-ancestry architecture remain unclear. <h4>Methods</h4> We analyzed African (AFR) and European (EU) ancestry datasets, including 9,965 asthma cases and 37,391 controls of AFR, and 6,074 cases and 116,255 controls of EU ancestry. Imputed dosage-based association analyses were p...

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Literature Corpus work: b771e91c-63c5-5bab-9282-c5b4a8407f10
DOI: 10.64898/2026.05.06.26352550

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