Article

Analysis of Chromatin Data Supports a Role For CD14+ Monocytes/Macrophages in Mediating Genetic Risk for Juvenile Idiopathic Arthritis

2022-07-14

Abstract excerpt

<h4>Introduction</h4> Genome wide association studies (GWAS) have identified multiple regions that confer genetic risk for the polyarticular/oligoarticular forms of juvenile idiopathic arthritis (JIA). However, genome-wide scans do not identify the cells impacted by genetic polymorphisms on the risk haplotypes or the genes impacted by those variants. We have shown that genetic variants driving JIA risk are likely...

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Literature Corpus work: b7551041-d6d9-5145-8bdf-532d56d3d0d1
DOI: 10.1101/2022.07.13.499916

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