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Article

Chromatin landscapes and genetic risk for juvenile idiopathic arthritis.

Arthritis research & therapy - 14 Mar 2017

Zhu Lisha, Jiang Kaiyu, Webber Karstin, Wong Laiping, Liu Tao, Chen Yanmin, Jarvis James N

Abstract excerpt

BACKGROUND: The transcriptomes of peripheral blood cells in children with juvenile idiopathic arthritis (JIA) have distinct transcriptional aberrations that suggest impairment of transcriptional regulation. To gain a better understanding of this phenomenon, we studied known JIA genetic risk loci, the majority of which are located in non-coding regions, where transcription is regulated and coordinated on a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28288683
DOI: 10.1186/s13075-017-1260-x
PMCID: PMC5348874

Genes

TRAF1

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