Article

An oncoembryology approach uncovers SoxC-driven regulation of colon development and cancer

2024-10-11

Abstract excerpt

Reactivated embryonic programs are associated with cancer progression, yet their role and regulatory mechanisms remain poorly understood. In this study, we introduce ‘oncoembryology,’ an approach that systematically compares embryonic and cancerous tissues to identify shared molecular programs and assess their functional relevance in disease. Applying this strategy to colorectal cancer, we identified SoxC transcri...

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Literature Corpus work: b72e2be8-c1f8-5ed0-a342-f154f43cee2a
DOI: 10.1101/2024.10.08.617191

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