Article
Transient telomerase inhibition alters cell cycle kinetics
2017-06-30
Abstract excerpt
<h4>ABSTRACT</h4> Telomerase is the ribonucleoprotein reverse transcriptase that catalyzes the synthesis of telomeres at the ends of linear human chromosomes and contributes to proper telomere-loop (T-loop) formation. Formation of the T-loop, an obligate step before cell division can proceed, requires the generation of a 3’-overhang on the G-rich strand of telomeric DNA via telomerase or C-strand specific nucleas...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- b6bd591c-a402-5db3-a0ba-b5447e0c8baf
- DOI
- 10.1101/158287