Article
Dynamics of human telomerase recruitment depend on template-telomere base-pairing
2017-11-10
Abstract excerpt
The reverse transcriptase telomerase adds telomeric repeats to chromosome ends to counteract telomere shortening and thereby assures genomic stability in dividing human cells. Key variables in telomere homeostasis are the frequency with which telomerase engages the chromosome end and the number of telomeric repeats it adds during each association event. To study telomere elongation in vivo we have established a l...
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Identifiers and source
- Literature Corpus work
- 09776c74-6edb-5be2-82c8-3ddd97312a57
- DOI
- 10.1101/217885