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Targeting telomerase-expressing cancer cells

18 Feb 2011

Abstract excerpt

• Targeting telomerase-expressing cancer cells • Human telomeres act as a mitotic clock • Telomerase expression and cellular lifespan - Telomerase inhibition to block tumour growth • Telomerase-targeted immunotherapy • Targeting telomerase-expressing cells with oncolytic viruses • Concluding remarks The role of telomeres and telomerase as a target for cancer therapeutics is an area of continuing interest. This...

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PMID: 21332640
DOI: 10.1111/j.1582-4934.2011.01279.x

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