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Multiomics Analyses Reveal Sex Differences in Mouse Renal Proximal Subsegments

9 Feb 2023

Abstract excerpt

SIGNIFICANCE STATEMENT: Sex-dependent differences in kidney function are recognized but the underlying molecular mechanisms are largely unexplored. Advances in genomics and proteomic technologies now allow extensive characterization of differences between the same cell types of males and females. Multiomics integrating RNA-seq, ATAC-seq, and proteomics data to investigate differences in gene expression, chromatin...

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PMID: 36758122
DOI: 10.1681/asn.0000000000000089

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