Article

Strain-dependent induction of primary bile acid 7-dehydroxylation by cholic acid

2022-02-15

Abstract excerpt

Bile acids (BAs) are steroid-derived molecules with important roles in digestion, the maintenance of host metabolism and immunomodulation. Primary BAs are synthesised by the host, while secondary BAs are produced by the gut microbiome through transformation of the former. Regulation of microbial production of secondary BAs is not well understood, particularly the production of 7-dehydroxylated BAs, which are the m...

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Literature Corpus work: b695a0fb-160e-55aa-a0d9-faaf874e2b07
DOI: 10.1101/2022.02.15.480494

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