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Strain-dependent inhibition of <i>Clostridioides difficile</i> by commensal <i>Clostridia</i> encoding the bile acid inducible <i>(bai)</i> operon

2020-01-23

Abstract excerpt

Clostridioides difficile is one of the leading causes of antibiotic-associated diarrhea. Gut microbiota-derived secondary bile acids and commensal Clostridia that encode the bile acid inducible ( bai ) operon are associated with protection from C. difficile infection (CDI), although the mechanism is not known. In this study we hypothesized that commensal Clostridia are important for providing colonization resi...

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Literature Corpus work
697e79e4-efd5-5f4a-a77b-b387f86495ca
DOI
10.1101/2020.01.22.916304
Open publication

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