Article
Strain-dependent induction of primary bile acid 7-dehydroxylation by cholic acid
2024-05-02
Abstract excerpt
<title>Abstract</title> <p><bold>Background</bold> Bile acids (BAs) are steroid-derived molecules with important roles in digestion, the maintenance of host metabolism, and immunomodulation. Primary BAs are synthesized by the host, while secondary BAs are produced by the gut microbiome through transformation of the former. Nevertheless, regulation of microbial production of secondary BAs is not well understood, p...
Topics
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- Clostridium difficile and Clostridium perfringens research
- Drug Transport and Resistance Mechanisms
- Folate and B Vitamins Research
- Gut microbiota and health
- Helicobacter pylori-related gastroenterology studies
- Metabolism and Genetic Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Steroid Chemistry and Biochemistry
Identifiers and source
- Literature Corpus work
- 06fabb4a-41f7-54ed-acf5-fe1ef3583311
- DOI
- 10.21203/rs.3.rs-4207886/v1
