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Pangenome analysis of <i>Clostridium scindens</i> : a collection of diverse bile acid and steroid metabolizing commensal gut bacterial strains

2024-09-06

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<h4>ABSTRACT</h4> Clostridium scindens is a commensal gut bacterium capable of forming the secondary bile acids deoxycholic acid and lithocholic acid from the primary bile acids cholic acid and chenodeoxycholic acid, respectively, as well as converting glucocorticoids to androgens. Historically, only two strains, C. scindens ATCC 35704 and C. scindens VPI 12708, have been characterized in vitro and in vivo to...

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Literature Corpus work
f1e5b85f-d314-5155-b33b-23d6ef92feb3
DOI
10.1101/2024.09.06.610859
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