Article

Bone marrow from focal segmental glomerulosclerosis displays activation of inflammatory pathway

2023-03-08

Abstract excerpt

Circulating factors resulting from immune dysfunction have been proposed as one of the causes for increased risk of graft loss associated with recurrence of focal segmental glomerulosclerosis (FSGS) after kidney transplant. However, the precise identity of the circulating factors and their sources remain incompletely characterized. In vivo studies in mouse models have implicated a role for immature bone marrow cel...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b684b744-c76e-5b44-90dc-280e05890e51
DOI: 10.1101/2023.03.06.23286859

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Bone marrow from focal segmental glomerulosclerosis displays activation of inflammatory pathwayDOI 10.1101/2023.03.06.23286859Read

Perturbations in podocyte transcriptome and biological pathways induced by FSGS associated circulating factorsSemantic proximity Read

The immune cell landscape in kidneys of lupus nephritis patientsSemantic proximity Read

FSGS Recurrence in Adults after Renal Transplantation.Semantic proximity Read

Perturbations in podocyte transcriptome and biological pathways induced by FSGS associated circulating factorsSemantic proximity Read

Single-Cell RNA Sequencing Reveals the Immunological Profiles of Renal Allograft Rejection in Mice.Semantic proximity Read

Intrarenal myeloid subsets associated with kidney injury are comparable in mice and patients with lupus nephritisSemantic proximity Read

Response to Steroid and Immunosuppressive Therapies May Predict Post-transplant Recurrence of Focal Segmental GlomerulosclerosisSemantic proximity Read

Single-Cell Transcriptomics of a Human Kidney Allograft Biopsy Specimen Defines a Diverse Inflammatory ResponseSemantic proximity Read

Urine single cell RNA-sequencing in focal segmental glomerulosclerosis reveals inflammatory signatures in immune cells and podocytesSemantic proximity Read

Deep profiling of lupus nephritis kidneys reveals dynamic changes in myeloid cells associated with disease progressionSemantic proximity Read

Multi-Omics Mapping of Human Kidney Reveals Complement-Mediated Cellular Dynamics During Progression of Focal Segmental GlomerulosclerosisSemantic proximity Read

A Molecular Profile of Focal Segmental Glomerulosclerosis from Formalin-Fixed, Paraffin-Embedded TissueSemantic proximity Read