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Article

Perturbations in podocyte transcriptome and biological pathways induced by FSGS associated circulating factors

5 May 2023

Abstract excerpt

Background: Focal segmental glomerulosclerosis (FSGS) is frequently associated with heavy proteinuria and progressive renal failure requiring dialysis or kidney transplantation. However, primary FSGS also has a ~40% risk of recurrence of disease in the transplanted kidney (rFSGS). Multiple circulating factors have been identified to contribute to the pathogenesis of primary and rFSGS including soluble...

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Share to Renal Diseases and Glomerulopathies
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PMID: 37404982
DOI: 10.21037/atm-22-3670

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