Article

The α<sub>2A</sub>-adrenergic receptor (<i>ADRA2A</i>) modulates susceptibility to Raynaud’s syndrome

2023-10-05

Abstract excerpt

Raynaud’s syndrome is a common dysautonomia where exposure to cold increases the vascular tone of distal arteries causing vasoconstriction and hypoxia, particularly in the extremities. Current treatment options are limited and unspecific. Biological mechanisms leading to the phenotype remain uncharacterized. Using genetic and electronic health record data from the UK Biobank, the Mass-General Brigham Biobank, the...

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Literature Corpus work: b681a2c7-8c9a-58ab-9a0a-0147b87b4a8f
DOI: 10.1101/2023.10.04.23296526

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