Article

High throughput and affordable genome-wide methylation profiling of circulating cell-free DNA by Methylated DNA sequencing (MeD-seq) of LpnPI digested fragments

2021-07-12

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> DNA methylation detection in liquid biopsies provides a highly promising and much needed means for real-time monitoring of disease load in advanced cancer patient care. Compared to the often-used somatic mutations, tissue- and cancer-type specific epigenetic marks affect a larger part of the cancer genome and generally have a high penetrance throughout the tumour. Here we de...

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Literature Corpus work: b678c15d-7edc-5fbb-afa1-fe08f31fc51d
DOI: 10.1101/2021.07.12.452012

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