Article

<i>De novo</i> design of high-affinity antibody variable regions (Fv) against the SARS-CoV-2 spike protein

2020-04-11

Abstract excerpt

The emergence of SARS-CoV-2 is responsible for the pandemic of respiratory disease known as COVID-19, which emerged in the city of Wuhan, Hubei province, China in late 2019. Both vaccines and targeted therapeutics for treatment of this disease are currently lacking. Viral entry requires binding of the viral spike receptor binding domain (RBD) with the human angiotensin converting enzyme (hACE2). In an earlier pape...

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Literature Corpus work: b630acb2-648c-53e0-b8a3-de8310dd91ff
DOI: 10.1101/2020.04.09.034868

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