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Article

Computational design of a neutralizing antibody with picomolar binding affinity for all concerning SARS-CoV-2 variants

14 Jan 2022

Abstract excerpt

Coronavirus disease 2019, caused by SARS-CoV-2, remains an on-going pandemic, partly due to the emergence of variant viruses that can "break-through" the protection of the current vaccines and neutralizing antibodies (nAbs), highlighting the needs for broadly nAbs and next-generation vaccines. We report an antibody that exhibits breadth and potency in binding the receptor-binding domain (RBD) of the virus spike...

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PMID: 35030983
DOI: 10.1080/19420862.2021.2021601

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