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Article

TRPM2: a potential drug target to retard oxidative stress.

Frontiers in bioscience (Landmark edition) - 1 Mar 2017

Li Jun, Gao Yunling, Bao Xianying, Li Fengna, Yao Wei, Feng Zemeng, Yin Yulong

Abstract excerpt

The Transient Receptor Potential Melastatin 2 (TRPM2) is a member of G protein coupled receptor superfamily and a novel dual-function protein that possesses both ion channel and Adenosine 5'-DiphosPhatase Ribose (ADPR) hydrolase function. TRPM2 is involved in Ca2+ signaling in various cells as an endogenous redox sensor for oxidative stress and reactive oxygen species, and contributes to cytokine production,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28199210
DOI: 10.2741/4551

Genes

TRPM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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