Article

Immunological imprinting shapes the cross-reactive antibody responses to the KP.2 and LP.8.1 vaccine doses

2026-05-15

Abstract excerpt

<h4>ABSTRACT</h4> The emergence of the SARS-CoV-2 Omicron BA.2.86 subvariant, a lineage derived from the BA.2 strain, led to the 2024-2025 COVID-19 vaccine update to include KP.2 or related JN.1-lineage spike antigens. We evaluated the magnitude, breadth, and durability of humoral immune responses following a single KP.2 vaccine dose in a longitudinal cohort of 21 individuals up to six months. KP.2 vaccination in...

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Literature Corpus work: 33c263c7-5dbd-5587-aea3-5a0853cb26ce
DOI: 10.64898/2026.05.13.725047

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