Back to search

Article

<i>Bacteroides</i> expand the functional versatility of a universal transcription factor and transcribed DNA to program capsule diversity

2024-06-21

Abstract excerpt

<h4>SUMMARY</h4> Human gut Bacteroides species encode numerous (eight or more) tightly regulated capsular polysaccharides (CPS). Specialized paralogs of the universal transcription elongation factor NusG, called UpxY (Y), and an anti-Y UpxZ (Z) are encoded by the first two genes of each CPS operon. The Y-Z regulators combine with promoter inversions to limit CPS transcription to a single operon in most cells. Y...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
b5ab2e89-8a09-5e27-bb43-48f973fca405
DOI
10.1101/2024.06.21.599965
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
<i>Bacteroides</i> expand the functional versatility of a universal transcription factor and transcribed DNA to program capsule diversityDOI 10.1101/2024.06.21.599965
Run-on sequencing reveals nascent transcriptomics of the human microbiomeSemantic proximity
Deep genome annotation of the opportunistic human pathogen <i>Streptococcus pneumoniae</i> D39Semantic proximity
Exapted CRISPR-Cas12f homologs drive RNA-guided transcriptionSemantic proximity
General Transcription Factor from <i>E. coli</i> with a Distinct Mechanism of ActionSemantic proximity
New genetic tools enable dissection of a global stress response in the early-branching species <i>Fusobacterium nucleatum</i>Semantic proximity
Open complex scrunching before nucleotide addition accounts for the unusual transcription start site of E. coli ribosomal RNA promoters.Semantic proximity
The RNA-binding protein RbpB is a central regulator of polysaccharide utilization in gut <i>Bacteroides</i>Semantic proximity
Hyperosmotic stress induces downstream-of-gene transcription and alters the RNA Polymerase II interactome despite widespread transcriptional repressionSemantic proximity
Interplay between nucleoid-associated proteins and transcription factors in controlling specialized metabolism in <i>Streptomyces</i>Semantic proximity
A family of RRM-1 RNA binding proteins enables cold adaptation and environmental resilience in <i>Bacteroides</i>Semantic proximity
R-loop-dependent promoter-proximal termination ensures genome stability.Semantic proximity
Deep genome annotation of the opportunistic human pathogen Streptococcus pneumoniae D39Semantic proximity
Select a neighboring publication to make it the new centre.