Article

Roles for the long non-coding RNA <i>Pax6os1</i> / <i>PAX6-AS1</i> in pancreatic beta cell identity and function

2020-07-17

Abstract excerpt

<h4>Aim/Hypothesis</h4> Long non-coding RNAs (lncRNAs) are emerging as crucial regulators of beta cell development and function. Here, we investigate roles for an antisense lncRNA expressed from the Pax6 locus (annotated as Pax6os1 in mice and PAX6-AS1 in humans) in beta cell identity and functionality. <h4>Methods</h4> Pax6os1 expression was silenced in MIN6 cells using siRNAs and changes in gene expression...

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Literature Corpus work: b5a5f1f8-1cb2-529b-bd33-9b26fb843a4e
DOI: 10.1101/2020.07.17.209015

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