Article

Dynamics, Electrostatics, and Thermodynamics of Base Pairing at the <i>LTR-III</i> Quadruplex:Duplex Junction

2024-01-22

Abstract excerpt

<h4>ABSTRACT</h4> G-quadruplexes (GQs) play key regulatory roles within the human genome and have also been identified to play similar roles in other eukaryotes, bacteria, archaea, and viruses. Human immunodeficiency virus 1 (HIV-1), the etiological agent of acquired immunodeficiency syndrome (AIDS), can form two GQs in its long terminal repeat (LTR) promoter region, each of which act to regulate viral gene expre...

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Literature Corpus work: b5654741-6e56-5278-acd2-fce6d3e4c566
DOI: 10.1101/2024.01.17.576154

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