Article
De novo peptide sequencing with InstaNovo: Accurate, database-free peptide identification for large scale proteomics experiments
2023-08-31
Abstract excerpt
Bottom-up mass spectrometry-based proteomics is challenged by the task of identifying the peptide that generates a tandem mass spectrum. Traditional methods that rely on known peptide sequence databases are limited and may not be applicable in certain contexts. De novo peptide sequencing, which assigns peptide sequences to the spectra without prior information, is valuable for various biological applications; yet...
Topics
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- Glycosylation and Glycoproteins Research
- Monoclonal and Polyclonal Antibodies Research
- Multiple Myeloma Research and Treatments
- Peptidase Inhibition and Analysis
- Protein purification and stability
- RNA and protein synthesis mechanisms
- Ubiquitin and proteasome pathways
- vaccines and immunoinformatics approaches
Identifiers and source
- Literature Corpus work
- eb77838f-d9ed-5830-a752-a366f41b6f72
- DOI
- 10.1101/2023.08.30.555055
